OncoStrands Search
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Precision Oncology Full Gene List
ESSENTIAL | DNA68 | EXTENDED | COMPREHENSIVE
Enter a Biomarker name to search:
Assay coverage for genes implicated (Mutations/CNVs/Fusions/MSI/TMB) in multiple cancer types with matched biomarker therapeutic recommendations (FDA, NCCN) as follows:
| Cancer Type | Biomarkers, DNA & RNA / Diagnostic / Predictive / Prognostic / Clinical Trial eligibility | Biomarkers with FDA-Approved Matched Therapy* | NCCN Biomarkers Compendium® Recommended Genes2 |
|---|---|---|---|
| Pan-Cancer | Pan Cancer Biomarkers (PCB): NTRK1, NTRK2, NTRK3 (fusions) MMR-d/MSI-H TMB-H | • MSI-H, TMB-H: Immunotherapy • NTRK1/2/3** fusions: TRK inhibitor therapy | • MSI-H, TMB-H: Immunotherapy • NTRK1/2/3 fusions: TRK inhibitor therapy |
| Lung | AKT1, ALK, BRAF, BRCA2, DDR2, EGFR, ERBB2, FGFR1, FGFR3, HRAS, KRAS, MAP2K1, MET, NRAS, PIK3CA, PTEN, RET, RICTOR, TP53 | ALK, BRAF, EGFR, KRAS, ROS1, RET, MET, Pan Cancer Biomarkers (PCB): NTRK1, NTRK2, NTRK3 (fusions) MMR-d/MSI-H TMB-H | ALK, BRAF, EGFR, ERBB2, KRAS, MET, RET, ROS1, Pan Cancer Biomarkers (PCB): NTRK1, NTRK2, NTRK3 (fusions) MMR-d/MSI-H TMB-H |
| Melanoma | BRAF, CTNNB1, GNA11, GNAQ, KIT, MAP2K1, NF1, NRAS, PDGFRA, PIK3CA, PTEN, TP53 | BRAF, Pan Cancer Biomarkers (PCB): NTRK1, NTRK2, NTRK3 (fusions) MMR-d/MSI-H TMB-H | BRAF, CDKN2A, KIT, NRAS |
| Colon | AKT1, APC, ATM, BRAF, CDH1, CHEK2, EGFR, ERBB2, HRAS, KRAS, MET, MLH1, MSH2, MSH6, MUTYH, NRAS, PIK3CA, PMS2, PTEN, SMAD4, STK11, TP53 | BRAF, RAS (wild type), MMR genes Pan Cancer Biomarkers (PCB): NTRK1, NTRK2, NTRK3 (fusions) MMR-d/MSI-H TMB-H | EGFR, KRAS, MMR genes, MUTYH, NRAS, PIK3CA, Pan Cancer Biomarkers (PCB): NTRK1, NTRK2, NTRK3 (fusions) MMR-d/MSI-H TMB-H |
| Ovarian and Fallopian tube | AKT1, ARID1A, ATR, BRAF, BRCA1, BRCA2, ERBB2, FOXL2, KRAS, PDGFRA, PTEN, RAD51C, TP53 | BRCA1, BRCA2, Pan Cancer Biomarkers (PCB): NTRK1, NTRK2, NTRK3 (fusions) MMR-d/MSI-H TMB-H HRD | BRCA1, BRCA2, Pan Cancer Biomarkers (PCB): NTRK1, NTRK2, NTRK3 (fusions) MMR-d/MSI-H TMB-H |
| Breast | AKT1, ATM, AR, BRCA1, BRCA2, CDH1, CHEK2, ERBB2, ESR1, FGFR1, FGFR2, MLH1, MSH2, MSH6, NBN, PALB2, PIK3CA, PMS2, PTEN, RAD51C, STK11, TP53 | BRCA1, BRCA2, ERBB2, PIK3CA, Pan Cancer Biomarkers (PCB): NTRK1, NTRK2, NTRK3 (fusions) MMR-d/MSI-H TMB-H | BRCA1, BRCA2, ERBB2, Pan Cancer Biomarkers (PCB): NTRK1, NTRK2, NTRK3 (fusions) MMR-d/MSI-H TMB-H |
| Oesophageal | ERBB2, MLH1, MSH2, MSH6, NTRK1, NTRK2, NTRK3, PMS2 | ERBB2, Pan Cancer Biomarkers (PCB): NTRK1, NTRK2, NTRK3 (fusions) MMR-d/MSI-H TMB-H | ERBB2, Pan Cancer Biomarkers (PCB): NTRK1, NTRK2, NTRK3 (fusions) MMR-d/MSI-H TMB-H |
| Gastric | ARID1A, BRAF, ERBB2, KIT, KRAS, MET, MLH1, PDGFRA, TP53 | ERBB2, Pan Cancer Biomarkers (PCB): NTRK1, NTRK2, NTRK3 (fusions) MMR-d/MSI-H TMB-H | CDH1, ERBB2, Pan Cancer Biomarkers (PCB): NTRK1, NTRK2, NTRK3 (fusions) MMR-d/MSI-H TMB-H |
| Bladder | ATM, ERBB3, FGFR2, FGFR3, MTOR, RB1, TSC1 | FGFR2, FGFR3, Pan Cancer Biomarkers (PCB): NTRK1, NTRK2, NTRK3 (fusions) MMR-d/MSI-H TMB-H | FGFR2, FGFR3, Pan Cancer Biomarkers (PCB): NTRK1, NTRK2, NTRK3 (fusions) MMR-d/MSI-H TMB-H |
| Pancreas | ARID1A, BRAF, BRCA1, BRCA2, CDK12, CDKN2A, EGFR, EP300, FBXW7, HRAS, KRAS, MLH1, MSH2, NOTCH1, NOTCH2, PALB2, PIK3CA, PTEN, STK11, TP53 | BRCA1, BRCA2, Pan Cancer Biomarkers (PCB): NTRK1, NTRK2, NTRK3 (fusions) MMR-d/MSI-H TMB-H | ALK, ATM, BRAF, BRCA1, BRCA2, CDKN2A, ERBB2, FGFR2, KRAS, MMR genes, NRG1, PALB2, RET, ROS1, STK11, TP53, Pan Cancer Biomarkers (PCB): NTRK1, NTRK2, NTRK3 (fusions) MMR-d/MSI-H TMB-H |
| Prostate | AR, ATM, ARD1A, BARD1, BRAF, BRCA1, BRCA2, BRIP1, CDKN2A, CDK12, CHEK1, CHEK2, FANCL, PALB2, PTEN, RAD51B, RAD51C, RAD51D, RAD54L, RAF1, TMPRSS2 | ATM, BARD1, BRCA1, BRCA2, BRIP1, CDK12, CHEK1, CHEK2, FANCL, PALB2, RAD51B, RAD51C, RAD51D, RAD54L, Pan Cancer Biomarkers (PCB): NTRK1, NTRK2, NTRK3 (fusions) MMR-d/MSI-H TMB-H | AR, ATM, BARD1, BRCA1, BRCA2, BRIP1, CDK12, CHEK1, CHEK2, FANCA, FANCL, HOXB13, MMR genes, PALB2, PPP2R2A, RAD51B, RAD51C, RAD51D, RAD54L, TMPRSS2 |
| Thyroid | BRAF, HRAS, KRAS, NRAS, PTEN, RET, | RET, Pan Cancer Biomarkers (PCB): NTRK1, NTRK2, NTRK3 (fusions) MMR-d/MSI-H TMB-H | ALK, BRAF, RET, Pan Cancer Biomarkers (PCB): NTRK1, NTRK2, NTRK3 (fusions) MMR-d/MSI-H TMB-H |
| Cholangiocarcinoma | BRAF, FGFR2, IDH1, KRAS | FGFR2, Pan Cancer Biomarkers (PCB): NTRK1, NTRK2, NTRK3 (fusions) MMR-d/MSI-H TMB-H | BRAF, BRCA1, BRCA2, ERBB2, FGFR2, IDH1, RET, Pan Cancer Biomarkers (PCB): NTRK1, NTRK2, NTRK3 (fusions) MMR-d/MSI-H TMB-H |
| GIST | APC, ARID1A, ATR, BRAF, EGFR, FGFR1, FGFR2, HRAS, KIT, KRAS, MET, MLH1, MSH2, MSH6, NF1, NRAS, PDGFRA, PMS2, STK11, SMAD4, TP53 | KIT, Pan Cancer Biomarkers (PCB): NTRK1, NTRK2, NTRK3 (fusions) MMR-d/MSI-H TMB-H | BRAF, FGFR1, KIT, NF1, NTRK1, NTRK2, NTRK3, PDGFRA, |
| Sarcoma | ALK, APC, BRAF, CDK4, CTNNB1, ETV6, EWSR1, FOX01, GLI1, KJT, MDM2, MYOD1, NAB2, NF1, PAX3, PAX7, PDGFRA, PDGFRB, SDHB, SDHC, SMARCB1, TFE3, WT1 | Various fusions, Pan Cancer Biomarkers (PCB): NTRK1, NTRK2, NTRK3 (fusions) MMR-d/MSI-H TMB-H | Various fusions, Pan Cancer Biomarkers (PCB): NTRK1, NTRK2, NTRK3 (fusions) MMR-d/MSI-H TMB-H |
| Thymic carcinoma | KIT | - | KIT |
| Head and Neck Squamous cancer | AR, ARID1A, BRAF, CDK12, CDKN2A, EGFR, EP300, ERBB2, FBXW7, FGFR1, FGFR2, FGFR3, HRAS, KRAS, NOTCH1, NOTCH2, PIK3CA, TP53 | Pan Cancer Biomarkers (PCB): NTRK1, NTRK2, NTRK3 (fusions) MMR-d/MSI-H TMB-H | ERBB2, HRAS, PIK3CA Pan Cancer Biomarkers (PCB): NTRK1, NTRK2, NTRK3 (fusions) MMR-d/MSI-H TMB-H |
| Brain | ALK, APC, ATRX, BRAF, CDKN2A, CDKN2B, CTNNB1, EGFR, H3-3A, H3C2, IDH1, IDH2, MET, MYC, NF1, NTRK, PDGFRA, RELA, TERT, TP53 | Pan Cancer Biomarkers (PCB): NTRK1, NTRK2, NTRK3 (fusions) MMR-d/MSI-H TMB-H | APC, ATRX, BRAF, CDKN2A, CDKN2B, CTNNB1, EGFR, H3-3A, H3C2, IDH1, IDH2, MET, MYC, NF1, NTRK, PDGFRA, RELA, TERT, TP53 |
| Cervical Cancer | Pan Cancer Biomarkers (PCB): NTRK1, NTRK2, NTRK3 (fusions) MMR-d/MSI-H TMB-H | Pan Cancer Biomarkers (PCB): NTRK1, NTRK2, NTRK3 (fusions) MMR-d/MSI-H TMB-H | Pan Cancer Biomarkers (PCB): NTRK1, NTRK2, NTRK3 (fusions) MMR-d/MSI-H TMB-H |
| Uterine/Endometrial | AKT1, ARID1A, BARD1, BRAF, CDK12, CDKN2A, FGFR1, FGFR2, FGFR3, NRG1, POLE | Pan Cancer Biomarkers (PCB): NTRK1, NTRK2, NTRK3 (fusions) MMR-d/MSI-H TMB-H | POLE, TP53, Pan Cancer Biomarkers (PCB): NTRK1, NTRK2, NTRK3 (fusions) MMR-d/MSI-H TMB-H Various fusions for uterine sarcoma |
*Matched therapy details are part of report contents for each patient
**Specific NTRK1, NTRK3 mutations with acquired resistance to TRK inhibitors are FDA listed contraindication for TRK inhibitors
1 NCCN, ASCO, ESMO, CIVIC, Jackson’s Laboratory, OncoKB, My Cancer Genome, current as of July 2022.
2 NCCN Biomarkers Compendium® viewed July 2022,
ESSENTIAL PANEL (50 genes)
DNA Hotspots (SNVs, Indels)
AKT1
AKT2
AKT3
ALK
AR
ARAF
BRAF
CDK4
CDKN2A
CHEK2
CTNNB1
EGFR
ERBB2
ERBB3
ERBB4
ESR1
FGFR1
FGFR2
FGFR3
FGFR4
FLT3
GNA11
GNAQ
GNAS
HRAS
IDH1
IDH2
KIT
KRAS
MAP2K1
MAP2K2
MET
MTOR
NRAS
NTRK1
NTRK2
NTRK3
PDGRFA
PIK3CA
PTEN
RAF1
RET
ROS1
SMO
TP53
ESSENTIAL PANEL (50 genes)
CNVs
ALK
AR
CD274
CDK2NA
EGFR
ERBB2
ERBB3
FGFR1
FGFR2
FGFR3
KRAS
MET
PIK3CA
PTEN
ESSENTIAL PANEL (50 genes)
RNA Fusions
ALK
AR
BRAF
EGFR
ESR1
FGFR1
FGFR2
FGFR3
MET
NRG1
NTRK1
NTRK2
NTRK3
NUTM1
RET
ROS1
RSPO2
RSPO3
DNA 68 PANEL (68 genes)
DNA (SNVs, Indels, CNVs)
AKT1
ALK
APC
AR
ARID1A
ATM
BRAF
BRCA1
BRCA2
BRIP1
CD274
CDH1
CDK4
CDK6
CDK12
CDKN2A
CHEK2
CTNNB1
EGFR
EPCAM
ERBB2
ESR1
FBXW7
FGFR1
FGFR2
FGFR3
FOXL2
GNA11
GNAQ
GNAS
HRAS
IDH1
IDH2
KEAP1
KIT
KRAS
MAP2K1
MDM2
MET
MUTYH
MLH1
MSH2
MSH6
MYC
NF1
NF2
NRAS
PALB2
PDGFRA
PDGFRB
PIK3CA
PMS2
POLE
POLD1
PTEN
RAF1
RB1
RET
ROS1
SF3B1
SMAD4
SMO
STK11
TERT*
TP53
TSC1
TSC2
VHL
EXTENDED PANEL (109 genes)
DNA (SNVs, Indels)
AKT1
ALK
APC
AR
ARID1A
ATM
ATR
BAP1
BARD1
BRAF
BRCA1
BRCA2
BRIP1
CDH1
CD274
CDK4
CDK6
CDK12
CDKN2A
CDKN2B
CHEK1
CHEK2
CSF1R
CTNNB1
CYSLTR2
DDR2
EGFR
EPCAM
ERBB2
ERBB3
ERCC2
ESR1
EZH2
FANCA
FANCL
FBXW7
FGFR1
FGFR2
FGFR3
FOXL2
GNA11
GNAQ
GNAS
HDAC2
HNF1A
HRAS
H3F3A#
H3F3B#
HIST1H3B#
HIST1H3C#
IDH1
IDH2
JAK2
KEAP1
KIT
KRAS
MAP2K1
MAP2K2
MET
MLH1
MRE11
MSH2
MSH6
MYC
MYCN
MTOR
MUTYH
NBN
NF1
NF2
NFE2L2
NOTCH1
NRAS
NTRK1
NTRK2
NTRK3
PALB2
PDGFRA
PDGFRB
PIK3CA
PMS2
POLD1
POLE
PPP2R1A
PPP2R2A
PTCH1
PTEN
PTPN11
RAD50
RAD51B
RAD51C
RAD51D
RAD54L
RAF1
RB1
RET
ROS1
SETD2
SF3B1
SMAD4
SMARCB1
SMO
SRC
STK11
TERT*
TP53
TSC1
TSC2
VHL
EXTENDED PANEL (109 genes)
CNVs
AKT1
ALK
APC
AR
ARID1A
ATM
ATR
BAP1
BARD1
BRAF
BRCA1
BRCA2
BRIP1
CDH1
CD274
CDK4
CDK6
CDK12
CDKN2A
CDKN2B
CHEK1
CHEK2
CSF1R
CTNNB1
CYSLTR2
DDR2
EGFR
EPCAM
ERBB2
ERBB3
ERCC2
ESR1
EZH2
FANCA
FANCL
FBXW7
FGFR1
FGFR2
FGFR3
FOXL2
GNA11
GNAQ
GNAS
HDAC2
HNF1A
HRAS
IDH1
IDH2
JAK2
KEAP1
KIT
KRAS
MAP2K1
MAP2K2
MET
MLH1
MRE11
MSH2
MSH6
MYC
MYCN
MTOR
MUTYH
NBN
NF1
NF2
NFE2L2
NOTCH1
NRAS
NTRK1
NTRK2
NTRK3
PALB2
PDGFRA
PDGFRB
PIK3CA
PMS2
POLD1
POLE
PPP2R1A
PPP2R2A
PTCH1
PTEN
PTPN11
RAD50
RAD51B
RAD51C
RAD51D
RAD54L
RAF1
RB1
RET
ROS1
SETD2
SF3B1
SMAD4
SMARCB1
SMO
SRC
STK11
TP53
TSC1
TSC2
VHL
COMPREHENSIVE PANEL (523 genes)
DNA (SNVs, Indels)
ABL1
ABL2
ACVR1
ACVR1B
AKT1
AKT2
AKT3
ALK
ALOX12B
ANKRD11
ANKRD26
APC
AR
ARAF
ARFRP1
ARID1A
ARID1B
ARID2
ARID5B
ASXL1
ASXL2
ATM
ATR
ATRX
AURKA
AURKB
AXIN1
AXIN2
AXL
B2M
BAP1
BARD1
BBC3
BCL10
BCL2
BCL2L1
BCL2L11
BCL2L2
BCL6
BCOR
BCORL1
BCR
BIRC3
BLM
BMPR1A
BRAF
BRCA1
BRCA2
BRD4
BRIP1
BTG1
BTK
C11orf30
CALR
CARD11
CASP8
CBFB
CBL
CCND1
CCND2
CCND3
CCNE1
CD274
CD276
CD74
CD79A
CD79B
CDC73
CDH1
CDK12
CDK4
CDK6
CDK8
CDKN1A
CDKN1B
CDKN2A
CDKN2B
CDKN2C
CEBPA
CENPA
CHD2
CHD4
CHEK1
CHEK2
CIC
CREBBP
CRKL
CRLF2
CSF1R
CSF3R
CSNK1A1
CTCF
CTLA4
CTNNA1
CTNNB1
CUL3
CUX1
CXCR4
CYLD
DAXX
DCUN1D1
DDR2
DDX41
DHX15
DICER1
DIS3
DNAJB1
DNMT1
DNMT3A
DNMT3B
DOT1L
E2F3
EED
EGFL7
EGFR
EIF1AX
EIF4A2
EIF4E
EML4
EP300
EPCAM
EPHA3
EPHA5
EPHA7
EPHB1
ERBB2
ERBB3
ERBB4
ERCC1
ERCC2
ERCC3
ERCC4
ERCC5
ERG
ERRFI1
ESR1
ETS1
ETV1
ETV4
ETV5
ETV6
EWSR1
EZH2
FAM123B
FAM175A
FAM46C
FANCA
FANCC
FANCD2
FANCE
FANCF
FANCG
FANCI
FANCL
FAS
FAT1
FBXW7
FGF1
FGF10
FGF14
FGF19
FGF2
FGF23
FGF3
FGF4
FGF5
FGF6
FGF7
FGF8
FGF9
FGFR1
FGFR2
FGFR3
FGFR4
FH
FLCN
FLI1
FLT1
FLT3
FLT4
FOXA1
FOXL2
FOXO1
FOXP1
FRS2
FUBP1
FYN
GABRA6
GATA1
GATA2
GATA3
GATA4
GATA6
GEN1
GID4
GLI1
GNA11
GNA13
GNAQ
GNAS
GPR124
GPS2
GREM1
GRIN2A
GRM3
GSK3B
H3F3A
H3F3B
H3F3C
HGF
HIST1H1C
HIST1H2BD
HIST1H3A
HIST1H3B
HIST1H3C
HIST1H3D
HIST1H3E
HIST1H3F
HIST1H3G
HIST1H3H
HIST1H3I
HIST1H3J
HIST2H3A
HIST2H3C
HIST2H3D
HIST3H3
HLA-A
HLA-B
HLA-C
HNF1A
HNRNPK
HOXB13
HRAS
HSD3B1
HSP90AA1
ICOSLG
ID3
IDH1
IDH2
IFNGR1
IGF1
IGF1R
IGF2
IKBKE
IKZF1
IL10
IL7R
INHA
INHBA
INPP4A
INPP4B
INSR
IRF2
IRF4
IRS1
IRS2
JAK1
JAK2
JAK3
JUN
KAT6A
KDM5A
KDM5C
KDM6A
KDR
KEAP1
KEL
KIF5B
KIT
KLF4
KLHL6
KMT2B
KMT2C
KMT2D
KRAS
LAMP1
LATS1
LATS2
LMO1
LRP1B
LYN
LZTR1
MAGI2
MALT1
MAP2K1
MAP2K2
MAP2K4
MAP3K1
MAP3K13
MAP3K14
MAP3K4
MAPK1
MAPK3
MAX
MCL1
MDC1
MDM2
MDM4
MED12
MEF2B
MEN1
MET
MGA
MITF
MLH1
MLL
MLLT3
MPL
MRE11A
MSH2
MSH3
MSH6
MST1
MST1R
MTOR
MUTYH
MYB
MYC
MYCL1
MYCN
MYD88
MYOD1
NAB2
NBN
NCOA3
NCOR1
NEGR1
NF1
NF2
NFE2L2
NFKBIA
NKX2-1
NKX3-1
NOTCH1
NOTCH2
NOTCH3
NOTCH4
NPM1
NRAS
NRG1
NSD1
NTRK1
NTRK2
NTRK3
NUP93
NUTM1
PAK1
PAK3
PAK7
PALB2
PARK2
PARP1
PAX3
PAX5
PAX7
PAX8
PBRM1
PDCD1
PDCD1LG2
PDGFRA
PDGFRB
PDK1
PDPK1
PGR
PHF6
PHOX2B
PIK3C2B
PIK3C2G
PIK3C3
PIK3CA
PIK3CB
PIK3CD
PIK3CG
PIK3R1
PIK3R2
PIK3R3
PIM1
PLCG2
PLK2
PMAIP1
PMS1
PMS2
PNRC1
POLD1
POLE
PPARG
PPM1D
PPP2R1A
PPP2R2A
PPP6C
PRDM1
PREX2
PRKAR1A
PRKCI
PRKDC
PRSS8
PTCH1
PTEN
PTPN11
PTPRD
PTPRS
PTPRT
QKI
RAB35
RAC1
RAD21
RAD50
RAD51
RAD51B
RAD51C
RAD51D
RAD52
RAD54L
RAF1
RANBP2
RARA
RASA1
RB1
RBM10
RECQL4
REL
RET
RFWD2
RHEB
RHOA
RICTOR
RIT1
RNF43
ROS1
RPS6KA4
RPS6KB1
RPS6KB2
RPTOR
RUNX1
RUNX1T1
RYBP
SDHA
SDHAF2
SDHB
SDHC
SDHD
SETBP1
SETD2
SF3B1
SH2B3
SH2D1A
SHQ1
SLIT2
SLX4
SMAD2
SMAD3
SMAD4
SMARCA4
SMARCB1
SMARCD1
SMC1A
SMC3
SMO
SNCAIP
SOCS1
SOX10
SOX17
SOX2
SOX9
SPEN
SPOP
SPTA1
SRC
SRSF2
STAG1
STAG2
STAT3
STAT4
STAT5A
STAT5B
STK11
STK40
SUFU
SUZ12
SYK
TAF1
TBX3
TCEB1
TCF3
TCF7L2
TERC
TERT
TET1
TET2
TFE3
TFRC
TGFBR1
TGFBR2
TMEM127
TMPRSS2
TNFAIP3
TNFRSF14
TOP1
TOP2A
TP53
TP63
TRAF2
TRAF7
TSC1
TSC2
TSHR
U2AF1
VEGFA
VHL
VTCN1
WISP3
WT1
XIAP
XPO1
XRCC2
YAP1
YES1
ZBTB2
ZBTB7A
ZFHX3
ZNF217
ZNF703
ZRSR2
COMPREHENSIVE PANEL (523 genes)
CNVs
AKT2
ALK
AR
ATM
BRAF
BRCA1
BRCA2
CCND1
CCND3
CCNE1
CDK4
CDK6
CHEK1
CHEK2
EGFR
ERBB2
ERBB3
ERCC1
ERCC2
ESR1
FGF1
FGF10
FGF14
FGF19
FGF2
FGF23
FGF3
FGF4
FGF5
FGF6
FGF7
FGF8
FGF9
FGFR1
FGFR2
FGFR3
FGFR4
JAK2
KIT
KRAS
LAMP1
MDM2
MDM4
MET
MYC
MYCL1
MYCN
NRAS
NRG1
PDGFRA
PDGFRB
PIK3CA
PIK3CB
PTEN
RAF1
RET
RICTOR
RPS6KB1
TFRC
COMPREHENSIVE PANEL (523 genes)
RNA Fusions
ABL1
AKT3
ALK
AR
AXL
BCL2
BRAF
BRCA1
BRCA2
CDK4
CSF1R
EGFR
EML4
ERBB2
ERG
ESR1
ETS1
ETV1
ETV4
ETV5
EWSR1
FGFR1
FGFR2
FGFR3
FGFR4
FLI1
FLT1
FLT3
JAK2
KDR
KIF5B
KIT
MET
MLL
MLLT3
MSH2
MYC
NOTCH1
NOTCH2
NOTCH3
NRG1
NTRK1
NTRK2
NTRK3
PAX3
PAX7
PDGFRA
PDGFRB
PIK3CA
PPARG
RAF1
RET
ROS1
RPS6KB1
TMPRSS2
COMPREHENSIVE RNA FUSIONS PANEL (501 genes)
ABI1
ABL1
ABL2
ACACA
ACE
ACER1
ACKR3
ACSL6
ADD3
AFF1
AFF3
AFF4
AGR3
AHI1
AHRR
ALK
ANKRD28
AR
ARHGAP20
ARHGAP26
ARNT
ASPSCR1
ASTN2
ATF1
ATIC
ATP1B4
AUTS2
BACH2
BAG4
BAIAP2L1
BAZ2A
BCAS3
BCAS4
BCL10
BCL11A
BCL11B
BCL2
BCL2L1
BCL3
BCL6
BCL9
BCOR
BCR
BDNF
BICC1
BIRC3
BIRC6
BRAF
BRD1
BRD3
BRD4
BRWD3
BTBD18
BTG1
C11orf1
C11orf95
C2CD2L
C3orf27
CAMTA1
CAPRIN1
CARS
CASC5
CASP7
CBFA2T3
CBFB
CBL
CCAR2
CCDC28A
CCDC6
CCDC88C
CCNB1IP1
CCNB3
CCND1
CCND2
CCND3
CD74
CDH11
CDK5RAP2
CDK6
CDX1
CDX2
CEBPA
CEBPB
CEBPD
CEBPE
CEP170B
CEP85L
CHD6
CHIC2
CHMP2B
CHST11
CIC
CIITA
CLP1
CLTC
CLTCL1
CMKLR1
CNBP
CNOT2
CNTRL
COG5
COL1A1
COL1A2
COL6A3
COX6C
CPSF6
CRADD
CREB1
CREB3L1
CREB3L2
CREBBP
CRLF2
CRTC1
CSF1
CSF1R
CTDSP2
CTNNB1
CUX1
DAB2IP
DACH1
DACH2
DDIT3
DDX10
DDX20
DEK
DMRT1
DNAJB1
DPM1
DUSP22
DUX4
EBF1
EEFSEC
EGFR
EGR1
EGR2
EGR3
EGR4
EIF4A2
ELF4
ELK4
ELL
ELN
EML1
EML4
EP300
EP400
EPC1
EPOR
EPS15
ERBB3
ERC1
ERCC1
ERG
ERLIN2
ESR1
ETS1
ETV1
ETV4
ETV5
ETV6
EWSR1
EZR
FAM19A2
FCGR2B
FCRL4
FEN1
FEV
FGF8
FGFR1
FGFR1OP
FGFR1OP2
FGFR2
FGFR3
FGFR4
FHIT
FIP1L1
FLI1
FLNA
FLT3
FLT3LG
FNBP1
FOSB
FOSL1
FOXO1
FOXO4
FOXP1
FRK
FRYL
FUS
GAS7
GATA1
GIT2
GLI1
GOSR1
GOT1
GPR128
GPR34
GRHPR
GRID1
GTF2I
H2AFX
HAS2
HEY1
HHEX
HIP1
HIPK1
HIST1H4I
HLF
HMGA2
HNF1A
HOXA10
HOXA11
HOXA13
HOXA9
HOXC11
HOXC13
HOXD11
HOXD13
HSP90AA1
ID4
IKZF1
IL2
IL21R
IL3
INPP5D
IQCG
IRF2BP2
IRF4
IRS4
ITK
JAK1
JAK2
JAZF1
KANK1
KAT6A
KAT6B
KDM5A
KIAA1524
KIF5B
KMT2A
KPNB1
KSR1
LASP1
LCK
LCP1
LGR5
LHFP
LHX2
LHX4
LMBRD1
LMO1
LMO2
LNP1
LPP
LPXN
LRMP
LRRC37B
LTBP1
LYL1
MACROD1
MAF
MAFB
MALT1
MAML2
MAPRE1
MBNL1
MBTD1
MDS2
MEAF6
MECOM
MGEA5
MKL1
MKL2
MLF1
MLLT1
MLLT10
MLLT11
MLLT3
MLLT4
MLLT6
MN1
MNX1
MSI2
MSN
MUC1
MUTYH
MYB
MYBL1
MYC
MYH11
MYH9
MYO18A
MYO1F
NAB2
NAPA
NBR1
NCOA1
NCOA2
NCOA3
NDE1
NF1
NFATC2
NFIB
NGF
NGFR
NIN
NIPBL
NKX2-5
NONO
NOTCH1
NPM1
NR4A3
NR6A1
NSD1
NT5C2
NTF3
NTF4
NTRK1
NTRK2
NTRK3
NUMA1
NUP107
NUP214
NUP98
NUTM1
NUTM2A
NUTM2B
OFD1
OLIG2
OLR1
OMD
P2RY8
PAPPA
PATZ1
PAX3
PAX5
PAX7
PAX8
PBX1
PCM1
PDE4DIP
PDGFB
PDGFRA
PDGFRB
PER1
PHF1
PHF23
PICALM
PIM1
PLAG1
PML
POM121
POU2AF1
POU5F1
PPAP2B
PPARG
PPARGC1A
PPFIBP1
PPP2R1B
PRCC
PRDM16
PRKACA
PRKAR1A
PRKG2
PRRX2
PSIP1
PSMD2
PTPRR
RABEP1
RAD51B
RAF1
RANBP2
RAP1GDS1
RARA
RBM15
RBM6
RCOR1
RCSD1
RET
RHOH
RNF213
ROS1
RPL22
RPN1
RREB1
RRM1
RTEL1
RUNX1
RUNX1T1
SARNP
SEC31A
SEPT2
SEPT5
SEPT6
SEPT9
SERPINE1
SERPINF1
SET
SETBP1
SFPQ
SH3D19
SH3GL1
SIK3
SLC34A2
SLC45A3
SLCO1B3
SMAP1
SMARCA5
SMARCB1
SORBS2
SORT1
SP3
SPECC1
SPTBN1
SQSTM1
SRF
SRSF3
SS18
SS18L1
SSBP2
SSX1
SSX2
SSX4
ST6GAL1
STAT5B
STAT6
STRN
SUGP2
SUZ12
SYK
TACC1
TACC2
TACC3
TAF15
TAL1
TAL2
TAOK1
TBX15
TCF12
TCF3
TCL1A
TCTA
TEAD1
TEAD2
TEAD3
TEAD4
TEC
TENM1
TET1
TFE3
TFG
TFPT
TFRC
TGFBR3
THADA
THRAP3
TIRAP
TLX1
TLX3
TMPRSS2
TNFRSF17
TOP1
TOP2B
TP53BP1
TPM3
TPM4
TRHDE
TRIM24
TRIP11
TRPS1
USP16
USP42
USP6
VGLL3
WASF2
WDR18
WDR70
WHSC1
WHSC1L1
WSB1
WT1
WWTR1
XIAP
YAP1
YTHDF2
YWHAE
ZBTB16
ZC3H7A
ZC3H7B
ZFP64
ZFPM2
ZFYVE19
ZMIZ1
ZMYM2
ZMYND11
ZNF207
ZNF384
ZNF444
ZNF521
ZNF585B
ZNF687